Statins’ benefits begin to sprout

Statins' benefits begin to sprout.

Efforts begin to sprout: publications in JCSM on cachexia, sarcopenia and muscle wasting receive attention

Does the world need a journal focusing on cachexia and sarcopenia, some asked in 2010 and 2011 when The Journal of Cachexia, Sarcopenia and Muscle (for short: JCSM) had just been launched. Today, we are looking back at 4 years of activity with more than 140 published reviews, editorials, letters and most importantly, original research articles. Particularly in the beginning, it was sometimes no...

Statins: is it really time to reassess benefits and risks?

search need. Evaluating the HBV viral load in HIV-infected pregnant women should be an essential step of prenatal evaluation, so that the mother’s health can be managed appropriately. Continued improvements in the coverage and timeliness of HBV vaccination and the education of clinicians about its importance should be priorities everywhere. Making such improvements will require substantial advo...

Benefits of statins beyond lipid lowering

Increasing evidence has accumulated suggesting that inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, or statins, have therapeutic ‘pleiotropic’ effects independent of cholesterol lowering. These include anti-inflammatory and antioxidative properties, improvement of endothelial function and increased nitric oxide bioavailability. In addition to elucidating underlying mech...

Lipid and nonlipid benefits of statins.

The Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (ATP III) provides an evidence-based approach to the diagnosis of dyslipidemia and the management of low-density lipoprotein cholesterol (LDL-C). This article provides a brief overview of the ATP III therapeutic approach (therapeutic life...